Tito Calì

Tito Calì is Full Professor at the Department of Biomedical Sciences, University of Padova.

 

2017: Assistant Professor, (RTDB) Department of Biomedical Sciences, University of Padova.

2015-2016: Assistant Professor, (RTDA) Department of Biomedical Sciences, University of Padova.

2013-2015: Senior Research Associate, University of Padova.

2009-2013: Junior Research Associate, University of Padova.

2008: PhD Degree “in signi cum laude”, Biochemistry/Molecular Biology, Theodor Kocher institute, University of Bern (CH) and Institute for Research in Biomedicine (IRB), Bellinzona (CH).

2005: Doctor in Biological Sciences 110/110 “Cum Laude”, Biochemistry/Molecular Biology, University of L’Aquila and Centre d’Immunologie Marseille Luminy (CIML).

 

Selected Publications

Calì T, et al. The ataxia related G1107D mutation of the plasma membrane Ca2+ ATPase isoform 3 affects its interplay with calmodulin and the autoinhibition process. BBA. 2017

Calì T, et al. A new split-GFP-based probe reveals DJ-1 translocation into the mitochondrial matrix to sustain ATP synthesis upon nutrient deprivation. HMG. 2015.

Calì T, et al. A Novel Mutation in Isoform 3 of the Plasma Membrane Ca2+ Pump Impairs Cellular Ca2+ Homeostasis in a Patient with Cerebellar Ataxia and Laminin Subunit 1? Mutations. JBC 2015.

Calì T, et al. Enhanced parkin levels favor ER-mitochondria crosstalk and guarantee Ca2+ transfer to sustain cell bioenergetics. BBA. 2013

Calì T, et al. ?-Synuclein controls mitochondrial calcium homeostasis by enhancing endoplasmic reticulum-mitochondria interactions. JBC. 2012

Zanni G, Calì T, et al. Mutation of plasma membrane Ca2+ ATPase isoform 3 in a family with X-linked congenital cerebellar ataxia impairs Ca2+ homeostasis. PNAS. 2012

Morten Gram Pedersen

Morten Gram Pedersen is Associate Professor in Bioengineering at the Department of Information Engineering, University of Padova.

 

He leads the unit for Modeling of Cell Biology. He holds a PhD in Mathematical Biology from the Technical University of Denmark, and has obtained independent funding for several postdoc positions, including a EU Marie Curie Intra-European Fellowships with Lund University Diabetes Centre, Malmö, Sweden.

 

He is the author of more than 50 papers on peer-reviewed journals (or which 8 as single author, 17 as first author; 30 as corresponding author). Besides collaborations with researchers from several departments of the University of Padova (Depts. Biomedical Sciences, Physics, Medicine, Mathematics), among others, he collaborates with experimental and theoretical researchers at Oxford University, UK; Uppsala University, Sweden; University of Exeter, UK; National Institutes of Health, MD, USA; Florida State University, FL, USA.

 

His main interests are mathematical modeling and theoretical analysis of:

  • local, intracellular calcium dynamics
  • local control of calcium-dependent potassium channels
  • protein and calcium dynamics evoking exocytosis of secretory vesicles
  • electrical activity in neuro-endocrine cells
  • clusters of electrically coupled cells