Aron Emmi

Currently, Aron Emmi serves as Assistant Professor of Human Anatomy at the Institute of Human Anatomy, Department of Neuroscience of the University of Padova, where he has previously obtained his degree and doctoral degree (PhD) and completed his post-graduate training in neuropathology and clinical neuroanatomy. He have also undergone post-doctoral training in forensic neuropathology.

 

His research activity focuses on the discovery and validation of central and peripheral neuropathological biomarkers for neurodegenerative diseases, particularly Parkinson’s Disease. Other research interests include clinical neuroanatomy of the human brainstem, nervous control of respiratory centers, infectious and inflammatory pathology of the brain and its relationship with neurodegeneration.

 

In the last 5 years Aron Emmi has published 50+ peer-reviewed articles in international journals in the field of neuroscience, neuropathology and human anatomy and presented his research activity as a speaker at over 60 national and international conferences. He serves as ad-hoc reviewer for several high-impact scientific journals (Nature NPJ Parkinson’s Disease, Movement Disorders, Journal of Neurology, Neurosurgery and Psychiatry, Neurobiology of Disease). He have co-authored 4 academic textbooks for students and specialists on neuroanatomy and microscopic anatomy.

 

Aron Emmi is a member of several national and international scientific organizations, including the Royal College of Pathologists, the European Confederation of Neuropathological Societies, and the italian group for neuromorphology.

Micaela Zonta

Micaela Zonta is Research Technologist at the Neuroscience Institute of the National Research Council in Padova.

 

She obtained her degree in Biology at the University of Padova and her PhD under the supervision of the CNR neuroscientist Giorgio Carmignoto, investigating how calcium signal in astrocytes regulates gliotransmitter release and functional hyperemia.

 

Her research group at the CNR Neuroscience Institute in Padua investigates the role of astrocytes in Alzheimer’s Disease mouse models and in the modulation of dopaminergic circuits.

 

Research interests
Our research interests focus on the characterization of Ca2+ signals in astrocytes from different brain circuits and in different brain pathological states. To pursue our aims, we combine 2 photon imaging, electrophysiological techniques and immunohistochemistry.

 

Our recent results reveal the contribution of astrocytes to synaptic modulation in the dopaminergic circuits of Ventral Tegmental Area, and the effects of early astrocyte Ca2+ dysregulation on somatosensory synaptic plasticity in a mouse model of Alzheimer’s disease (B6.152H).

 

We are actually studying Ca2+ signals in hippocampal astrocytes from α7 nicotinic acetylcholine receptor knockout mice, characterized by an age-dependent Alzheimer’s disease-like phenotype, and in parallel we are deepening Ca2+ signal characterization in astrocytes from the Ventral Tegmental Area.

 

In a recently funded Telethon project, we are exploring cerebrovascular function in the B6.152H Alzheimer’s mouse model, to disclose possible links existing between the impairment observed in astrocyte Ca2+ signal and the different aspects of vascular dysfunction commonly reported in Alzheimer’s disease.

 

ORCID: https://orcid.org/0000-0002-9982-6405

Ramón Guevara

Ramón Guevara is currently a Research Technologist at the Department of Physics and Astronomy, University of Padua, Italy.

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Marco Solmi

Marco Solmi is working with a Researcher position at University of Padua, and as a Psychiatrist at University Hospital of Padua.

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