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Padova Neuroscience Center

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‘Little brain’, big contributions – Reflection on cerebellar circuitry in action, perception, and cognition

by prof. Sonja Kotz – University of Maastricht

When: July 7th, 2022 – 3:00 pm

Where: Sala Seminari, VIMM. Recording available on Mediaspace

Abstract: It is well established that cortico-cerebellar-cortical circuitry monitors motor behavior, but recent evidence established that this circuitry similarly engages in the temporal encoding of basic and more complex (multi)sensory information. Consequently, cerebellar computations may generally apply to the temporal encoding of motor and basic and complex (multi)sensory information as (i) such information stimulates and monitors cortical information processing, and (ii) cerebellar-thalamic output might be a possible source of endogenous activity, predicting the outcome of cortical information processing and (iii) possibly providing a temporal frame for the binding of information.

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Thalamic regulation of prefrontal dynamics for cognitive control

by prof. Michael Halassa – MIT, Boston

When: June 23th, 2022 – 3:00 pm

Where: Sala Seminari, VIMM. Recording available on Mediaspace

Abstract: Interactions between the thalamus and cortex are critical for normal cognition. Although classical theories emphasize its role in transmitting signals to or between cortical areas, recent studies show that the thalamus modulates cortical function through additional mechanisms. In this talk, I will discuss findings that highlight the role of the mediodorsal (MD) thalamus in regulating prefrontal excitatory/inhibitory balance and effective connectivity during decision making. I will present recently published data showing that the MD thalamus dynamically adjusts prefrontal evidence integration according to incoming stimulus statistics.

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From synapse to network: models of information storage and retrieval in brain networks

by prof. Nicolas Brunel, Duke University

When: June 16th, 2022 – 3:00 pm

Where: VIMM Meeting room – Recording available on Mediaspace

Abstract: Brains have a remarkable ability to store information about the external world, on time scales that range from seconds to the lifetime of an animal. What are the mechanisms by which information is stored in the brain, and how is stored information retrieved from memory? One of the central hypothesis of neuroscience is that information is stored through synaptic plasticity – modifications of synaptic connectivity between neurons. Theoretical models have explored the impact of such synaptic plasticity mechanisms on network dynamics.

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Settimana per l’epilessia – 30 Maggio – 7 giugno 2022

L’Associazione Fuori dall’Ombra promuove la settimana dell’epilessia per migliorare le condizioni di salute di vita della popolazione affetta dalle varie forme di epilessia, con particolare attenzione alla rimozione dei pregiudizi sociali discriminatori, al diritto allo studio e all’inserimento nel mondo del lavoro.

https://www.fuoridallombra.org/2022/04/14/settimana-per-l-epilessia-2022/

settimana-epilessia-2022Download
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Deciphering how cortical astrocytes dynamically regulate synaptic plasticity ensuring the information storage in memory circuits

by prof. Marco Canossa, CIBIO, University of Trento

When: June 9th, 3:00 PM

Where: Aula 0B, Complesso di Biomedicina, Fiore di Botta, Padova

Abstract: In the cerebral cortex neurons are organized in specific layers and form connections both within the cortex and with other brain regions, thus forming a network of synaptic connections comprising distinct circuits. Plasticity is a fundamental feature of neuronal connections in the brain, where experience-dependent changes in synaptic strengths are crucial for creating learning and memory circuits (engrams). Deciphering how neurons dynamically express synaptic plasticity while ensuring the formation of memory circuits remains a key challenge. Glial cells respond to neuronal activation and release neuroactive molecules (termed “gliotransmitters”) that can affect synaptic activity and modulate plasticity.

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A diurnal rhythm of intracellular chloride in pyramidal neurons affects cortical dynamics and signal processing in the cortex

by prof. Gian Michele Ratto, Consiglio Nazionale delle Ricerche, Pisa

When: May 26th, 2022 – 3:00 pm

Where: Sala Seminari at VIMM. Recording available on Mediaspace

Abstract: Living organisms navigate through a cyclic world: activity, feeding, social interactions
are all organized along the periodic daily rhythm synchronized by external environmental cues and
brain function varies markedly through the day. An obvious contributory factor is the large change
in the level of sensory drive from day to night. Less obvious is the degree to which intrinsic
neuronal activity might vary, yet there is abundant clinical data supporting the idea that many
functional neurological and psychiatric conditions have strong diurnal patterns.

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HDEEG Facility

The Geodesic EEG system can acquire a 256 channel EEG.

Acquisitions can be done through two available networks:

  • HydroCel GSN Sensor NETs, MR compatible (available sizes: 54-56 cm, 56-58cm)
  • HydroCel GSN Sensor NETs, not MR compatible (available sizes: 54-56 cm, 56-58cm)

Networks are connected to a Net Amps 400 amplifier:

Feature Net Amps 400
Coupling DC
Chip for A/D conversion ADS1298
A/D resolution 24 bits
On-board microprocessor Intel ATOM 1.6 GHz 32-bit
FPGA DSP FIR filter signal processor
Embedded operating system Linux
I/O connection Fiber optic ethernet
Digital (TTL) inputs 16 bits (8 supported in hardware)
Input impedance ≥ 1 G ohm
Sensitivity (AC model)/precision 0.023 µV/bit
Bandwidth DC to 2000 Hz
Input noise < 0.8 µVRMS
Input range ± 200 mV
Common mode rejection rate ≥ 90 dB
Isolation mode rejection rate ≥ 120 dB
Sampling rate supported 8 KHz* (available: 0.25, 0.5, 1 KHz)
Power consumption 15 Watts
*Amp Server PRO SDK is required to realize the highest sampling rates

Also available are:

  • 2 GES Clock Sync I/O
  • 2 MR compatible electrodes for ECG measurements
  • E-Prime Experiment Control System for stimulus presentation
  • Faraday Cage
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Neuroscience PhD Retreat 2022

Neuroscience PhD Retreat will take place on 20 and 21 May in Asiago, Vicenza: the right moment for PhD students and faculty for sharing their ideas, perspectives and experience. There will be a focus on the goals already achieved, improvement suggestions and the path ahead.

PhD-Neuroscience-final2-1Download
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A Padova arriva la nuova macchina per la risonanza magnetica a 7 Tesla

(Italian version only) Article on “Il Mattino di Padova”, April 24th, 2022

20220421_IlMattino-Edificio-7-TeslaDownload

(Italian version only) Article on “Il Corriere del Veneto”, April 24th, 2022

20220421_IlCorriereDelVeneto-Edificio-7-TeslaDownload

(Italian version only) Article on “Padova Oggi”, April 24th, 2022

20220421_PadovaOggi-Edificio-7-TeslaDownload

(Italian version only) Article on “Il Gazzettino”, April 24th, 2022

20220421_IlGazzettino-Edificio-7-TeslaDownload
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Plasticity of visual representations in the mouse cortex

by prof. Andrea Benucci, RIKEN Center for Brain Science – Saitama – Japan

When: April 28th, 2022 – 10:00 am

Where: Zoom meeting. Recording available on Mediaspace

Abstract: In this presentation, I will first introduce the main areas of interest of my laboratory at RIKEN Center for Brain Science. Then, I will focus on a recent work where we examined the plasticity of visual representations in the mouse cortex.

The starting observation for this study is that brain circuits acquire and update computations through the dynamics of recurrently connected neurons. Neuronal connections are plastic but the principles that coordinate cell-to-cell connectivity changes for network-level computations remain largely elusive.

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  • Research
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      • By Research Topic
      • By Dept. / Structure
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  • PhD in Neuroscience
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    • Individual Training Plan
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    • Teaching Activities
    • PhD Students
    • Guidelines and Forms
  • News & Events
    • Events
    • News and Press release
  • Working @ PNC
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    • Invitations to tenants
    • Past Available Positions

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