by prof. Fritjof Helmchen, Brain Research Institute of the University of Zurich, Switzerland
When: Apr 29th, 2021 – 3:00 pm
Where: Zoom meeting ( https://bit.ly/3d32f16 )
Abstract: Through the combination of in vivo optical imaging and chronic expression of genetically encoded calcium indicators it is now feasible to directly ‘watch’ brain activity patterns related to specific behaviors. I will introduce wide-field calcium imaging and multi-fiber photometry as two complementary methods that enable measurements across mouse neocortex and in large sets of subcortical regions, respectively. Specific patterns of brain-wide signal flow that occur in mice performing whisker-based or auditory sensory discrimination tasks will be discussed, highlighting salient patterns related to short-term memory.