News & Events (90)

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Events (76) News and Press release (93)

Infezione da West Nile Virus: Aggiornamenti su epidemiologia, patogenesi e diagnosi

Relatrice: Prof.ssa Luisa Barzon, Dipartimento di Medicina Molecolare, Università di Padova

Quando: 21 febbraio 2023 dalle ore 16:00

Dove: Aula Magna della Clinica Neurologica.

Informazioni utili: L’incontro si articolerà in due parti. Nella prima, dalle ore 16:00 alle 17:00, ci sarà la presentazione e la discussione dei dati raccolti in Neurologia lo scorso anno durante l’ultimo outbreak di WNV. Nella seconda, dalle ore 17.30 alle 18.30, ci sarà il seminario.Ci sarà anche la possibilità di seguire i seminari in streaming (https://unipd.zoom.us/j/88959319767).

Luisa BarzonDownload

Structural and functional features of treatment-resistant depression: A systematic review and exploratory coordinate-based meta-analysis of neuroimaging studies

Alessandro Miola

A third of people suffering from major depressive disorder do not experience a significant improvement in their symptoms even after adequate treatment with two different antidepressant medications.

This common condition, termed treatment-resistant depression (TRD), severely affects the quality of life of millions of people worldwide. TRD is of utmost clinical relevance given the impact of residual depressive symptoms on functioning, the higher risk of recurrence, the lower chances of remission, and the risk of suicide (which is at least twice the rate of those with nonresistant depression), causing long-lasting interpersonal problems and social costs. Given its epidemiological and clinical relevance and the little consensus on whether the neurobiological underpinnings of TRD differ from treatment-sensitive depression (TSD), we aimed to highlight the convergent morphometric and functional neuroimaging correlates of TRD.

Beyond body image: what body schema and motor imagery can tell us about the way patients with anorexia nervosa experience their body

Valentina Meregalli
Elena Tenconi

Recent evidence suggests that the body image disturbances often observed in patients with anorexia nervosa also extends to the body schema. According to the embodiment approach, the body schema is not only involved in motor execution, but also in tasks that only require a mental simulation of a movement such as motor imagery, mental rotation of bodies, and visuospatial perspective-taking. The aim of the present study was to assess the ability of patients with anorexia in mentally simulate movements.

Enrico Collantoni
Angela Favaro
Paolo Meneguzzo

The sample included 52 patients with acute anorexia and 62 healthy controls.

Antagonistic effect of cyclin-dependent kinases and a calcium-dependent phosphatase on polyglutamine expanded androgen receptor toxic gain of function

Maria Pennuto
Fabio Sambataro

Spinal and bulbar muscular atrophy (SBMA) is a neurodegenerative disorder caused by the abnormal expansion of polyglutamine (PolyQ)-encoding CAG triplets in the androgen receptor (AR) gene. AR binds to testosterone and its more potent derivative dihydrotestosterone (DHT), which trigger the activation of androgen receptor and the transcription of genes responsive to testosterone. Several enzymes in the cells (called kinases) can add chemical modifications (phosphorylation) to transcription factors to tightly regulate specific gene expression programs. On the contrary, phosphatases do the opposite job and remove phosphorylation from these proteins. Working together in a concerted way, kinases and phosphatases modify stability, cellular localization and function of transcription factors.

The way we were, the way we will be. Open science: a change in the scientific paradigm.

by prof. Massimo Grassi, Dept. of General Psychology, University of Padova

When: January 10th, 2023 – 9:30 am

Where: Aula Magna della Clinica Neurologica. Recording available on Mediaspace

Abstract: If we imagine a scientist sleeping for 15 years and waking up today we can just guess his/her surprise: open access journals, papers that are published along with accessible repositories where authors make available the data, the codes that they used to analyze the data and all the relevant digital materials. Even peer reviews are available to the reader, not to mention pre-registration documents that reveal step by step the origin of scientific path followed by the author!

Adaptive neural networks in resting human brain explains coexistence of avalanches and oscillations

by dr. Fabrizio Lombardi, Institute of Science and Technology Austria (ISTA) – Vienna

When: December 1st, 2022 – 3:00 pm

Where: Sala Seminari – VIMM. 50 seats available. Mask is mandatory. Registration Link

Abstract: Neurons in the brain are wired into adaptive networks that exhibit a range of collective dynamics. Oscillations, for example, are paradigmatic synchronous patterns of neural activity with a defined temporal scale. Neuronal avalanches, in contrast, are scale-free cascades of neural activity, often considered as evidence of brain tuning to criticality. While models have been developed to account for oscillations or avalanches separately, they typically do not explain both phenomena, are too complex to analyze analytically, or intractable to infer from data rigorously.

Book presentation: “Alfonso Corti. The discovery of the hearing organ”

Proff. Alessandro Martini, Paolo Mazzarello, Eugenio Mira, and Albert Mudry – School of Medicine – Padova

When: November 22nd, 5:00 pm, 2022

Where: Aula Morgagni del Policlinico, Via Giustiniani 2, Padova

Abstract: In this book the biography is followed by a synopsis of scientists who followed in Alfonso Corti’s footsteps through the present, offered together with beautiful anatomic reproductions of Corti’s organ. Important followers were Nobel Prize winner Santiago Ramón y Cajal and Swedish anatomist Gustaf Retzius, nominated for the Nobel Prize nine times. Several others have provided new insights into the physiology, biochemistry, and especially, genetics involved in the coordinated development of this organ.

ERC synergy grant: 10 milioni di euro al progetto Unipd ‘Nemesis’

I proff. Corbetta, Deco, Massimini e Sanchez-Vivez

Professore di Neurologia dell’Università di Padova e direttore della Clinica Neurologica dell’Azienda Ospedaliera, è Maurizio Corbetta a ottenere, con un gruppo composto da altri 3 Principal Investigators provenienti dall’Università Statale di Milano e dall’Università Pompeu Fabra e l’ICREA di Barcellona, un finanziamento di quasi 10 milioni di Euro nello schema Synergy Grant

https://www.unipd.it/news/erc-synergy-grant-10-milioni-euro-progetto-nemesis-universit-padova

Predictive processing in spoken language comprehension: insights from electrophysiology in typical and atypical populations

by dr. Simone Gastaldon, Dept. of Developmental Psychology and Socialisation and Padova Neuroscience Center – Padova

When: November 3rd, 2022 – 3:00 pm

Where: Sala Seminari – VIMM. Recording available on Mediaspace.

Abstract: Understanding language is a complex task that neurologically intact people seem to perform very easily. To achieve this, our brain does not only passively process incoming stimuli, but also proactively predicts upcoming information to facilitate processing. In this talk I will present past and ongoing studies that investigate some aspects of such predictive processes, by using electroencephalography with both typically developed adults, and people with atypical development.